Medically reviewed by Jessica Swirble, PharmDLast updated on April 17, 2025
Drug Information| | |
Thyroxine hydrochloride is a selective serotonin reuptake inhibitor (SSRI) that increases the levels of hormones that control sex desire and may also help with the management of symptoms of hypoactive sexual desire in men and women. It is prescribed for conditions like:
Thyroxine hydrochloride is a second-generation anti-androgen that is approved by the FDA for use in the treatment of hypoactive sexual desire and erectile dysfunction. It is prescribed for conditions such as:
The combination of thyroxine hydrochloride and an ACE inhibitor does not result in the same therapeutic effects as the combination of an ACE inhibitor and an HRT. Thyroxine hydrochloride may result in fewer side effects compared to thyroxine hydrochloride alone.
Thyroxine hydrochloride is prescribed to treat symptoms of hypoactive sexual desire and erectile dysfunction. The side effects of thyroxine hydrochloride are similar to those seen with an ACE inhibitor. For conditions like
Thyroxine hydrochloride is used with an ACE inhibitor to treat symptoms of hypoactive sexual desire and erectile dysfunction. It is usually taken orally about 1 to 3 times a day with the evening notice. It is usually taken with a full glass of water. The benefits of taking thyroxine hydrochloride with an ACE inhibitor are similar to those seen with an ACE inhibitor alone.
Thyroxine hydrochloride is usually taken orally about 1 to 3 times a day with the evening notice.
Thyroxine hydrochloride may increase your risk of conditions that affect hormones in men. Examples include irregular or heavy menstrual periods, endometriosis, and breast cancer. You should inform your doctor if you have any of these and any other conditions before taking thyroxine hydrochloride.
Thyroxine hydrochloride is usually taken with a full glass of water. It also may be taken with or without food.
The risks of thyroxine hydrochloride and an ACE inhibitor are similar to those seen with an ACE inhibitor alone. However, thyroxine hydrochloride may cause fewer side effects compared to thyroxine hydrochloride alone.
Thyroid hormones are essential for regulating mood, heart, and kidney health. When hormones are low, they can bind to specific receptors and activate signaling pathways that control mood, energy, and metabolism. Thyroid hormones play a key role in regulating metabolism, energy use, bone health, heart health, and sperm quality.
Synthroid, the brand name for levothyroxine, was introduced in the 1960s. It was a first-line treatment for hypothyroidism, a condition in which the thyroid gland does not produce enough thyroid hormone. When the thyroid hormone replacement drug Synthroid was discontinued due to side effects, it became an attractive option for individuals with hypothyroidism.
Several clinical applications for thyroid hormone replacement medications are pending in the United States. These applications include:
Forms of thyroid hormone replacement therapy include:
Despite its clinical applications, the long-term risks of untreated hypothyroidism remain a concern for many patients. Issues such as osteoporosis and increased risk of cardiovascular events like heart attack and stroke have resulted in the use of levothyroxine replacement therapy in individuals who cannot tolerate subcutaneous doses of levothyroxine. Although the safety profile of levothyroxine replacement therapy is not well established, several clinical trials have demonstrated significant benefits for patients with hypothyroidism.
Patients with hypothyroidism should not use levothyroxine replacement therapy and should consult their healthcare provider before starting treatment. Patients with diabetes, heart disease, or a history of stroke should also exercise caution when using levothyroxine replacement therapy due to the risk of cardiovascular events. Patients with thyroid disorders, including hypothyroidism, should also be evaluated carefully for adverse reactions to their thyroid hormones.
In the years to come, the benefits of thyroid hormone replacement therapy may be evident. However, further research and evaluation are needed to establish the long-term safety and long-term efficacy of this approach in individuals with hypothyroidism.
References:is a generic version of Synthroid, Levoxyl, Unithyroid, Tirosint, andEuthyrox, among other names. Both generic and brand name medications are used to treat “hypothyroidism”, a condition where your body is not producing enough “thyroid hormone”. Your hormones control many of your bodily functions, so not having enough can cause many problems. Levothyroxine is the go-to treatment for hypothyroidism and works by “replacing” the missing thyroid hormones in your body.
Store medication in a cool, dry place, tak your medication below 30°F ( gone beyondstable and not needed.
The recommended starting dose of Levothyroxine is 300 to 500 milligrams (mg) once daily. Your doctor may increase your dose to 5, or you can prescribe a dose different from the tablet you are taking for two1016 times as prescribed (by comparsion)
Side effects can include bone pain, weight gain, increase in blood pressure, or severe allergic reactions. Some people may experience sleepicular movement, which can cause tiredness, drowsiness, or difficulty sleeping. Some problems can occur only if taked doses are used. If you experience any of these side effects or have any questions about taking any prescription medication, consult your doctor.
Some drugs can increase synthroid’s stability compared to biological standards. Tell your doctor if you are taking any of your medications that can cause an increase in blood thyroid levels. Some over-the-counter cough and cold medications include medicines you may not be aware of. Tell your doctor if you are taking any of your supplements that can increase your synthroid blood levels.
Levothyroxine can cause serious problems if you are not careful. If you are pregnant, if you are breast-feeding women, or if you are allergic to levothyroxine. Tell your doctor if you are pregnant or are breast-feeding or if you are taking any medication. Unnecessary use can lead to harm to your baby. Levothyroxine is excreted in breast milk. Do not use levothyroxine if you are breast-feeding. Before taking levothyroxine, tell your doctor about your child's medical history, including any other medications you are using, especially: kidney disease, thyroid disease, diabetes, high blood pressure, or an imbalance of thyroid hormone in your blood. This can make your child more sensitive to the side effects of levothyroxine.
Drugs that can increase synthroid stability include: certain HIV drugs, such as ritonavir, indinavir, lopinavir, nelfinavir, and telithromycin, certain medications used to treat certain cancers, such as and hormone therapy, certain antidepressants, certain antibiotics, certain antibiotics for HIV infection, some antibiotics, and a variety of over-the-counter supplements and medications that may increase synthroid levels, or certain medications that cause low blood thyroid levels, such as amiodarone, cisapride, fluvoxamine, diazepam, herpeticis, and klonopin. These can reduce the effectiveness of levothyroxine and increase the risk of side effects.
Levothyroxine is not recommended in pediatric patients. Levothyroxine is available only by prescription in the United States. Your doctor will discuss the risks and benefits with you before prescribing. The dosage of Levothyroxine prescribed in your child’s doctor’s office will be determined by the pediatrician based on the patient's weight and height.
Levothyroxine PrescriptionStore Levothyroxine medication in a cool and dry place away from direct sunlight. When you take levothyroxine, it converts to the thyroid hormone thyroxine (T4) at 300 mg per tablet, which is what it is made of. Levothyroxine is not available in the United States without a prescription. Check with your doctor to ensure that you are not breaking any laws and you are taking the medication. Do not store above 25° to 30°F (7.5 to 8.5 to 11.5 to 3.
Synthroid tablets are a medication used to treat hypothyroidism. It is a form of thyroid hormone replacement therapy. It works by replacing the missing thyroid hormone, which is not necessary in the thyroid gland. Synthroid tablets come in various strengths, including 25mcg, 50mcg, 75mcg, 88mcg, 100mcg, 112mcg, 125mcg, 137mcg, 150mcg, 175mcg, 200mcg, and 300mcg. Some may also take capsules, taken by mouth, for weight management. It is important to follow your doctor’s instructions when taking Synthroid tablets.
Take Synthroid tablets exactly as your doctor or pharmacist has told you. Do not crush, chew, or break the tablets. Swallow the tablet whole with a glass of water. Take your Synthroid tablets at the same time every day. Do not take your Synthroid tablets for longer than four hours without talking to your doctor or pharmacist. Your Synthroid tablets may be taken with or without food. You may need to take Synthroid tablets for the full prescribed duration.
If you are on levothyroxine, Synthroid tablets may be taken with or without food. If you are on Synthroid, your Synthroid may be taken with or without food, but you must wait at least 4 hours before eating.
Do not crush, break, or chew your Synthroid tablet. If you are taking levothyroxine, your Synthroid may be taken with or without food. If you are taking Synthroid, your Synthroid may be taken with or without food. Synthroid tablets may be taken with or without food.
You may also need to take Synthroid for the full prescribed duration. Do not stop taking your Synthroid without talking to your doctor. Synthroid tablets may be taken for the duration prescribed by your doctor. It is important to continue taking Synthroid tablets even if you feel well. Synthroid tablets should not be used for more than 4 weeks without talking to your doctor.
You should not use Synthroid tablets if you are allergic to levothyroxine, including levothyroxine sodium, or if you have diabetes, thyroid cancer, or have a history of diabetes. If you have or have ever had an organ transplant, you must speak to your doctor before taking Synthroid tablets.
Inform your doctor or pharmacist if you are currently taking any other medication, including any that contain nitrates or amyl nitrite.
Synthroid Tablets - Product InformationSynthroid tablets contain L-citrulline salt, which is a type of L-tryptophan. This means that Synthroid tablets contain L-citrulline, which is an amino acid that helps the body to absorb L-tryptophan. Synthroid tablets contain L-tryptophan, which is a sugar that can cause Synthroid tablets to absorb too much L-tryptophan. Synthroid tablets contain lactose, which means that Synthroid tablets contain lactose. If you are not sure if you are taking any prescription or nonprescription medicine, ask your doctor or pharmacist.
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